Part 1: The Clinical Laboratory

1. General Concepts and Administrative Issues

2. Optimizing Laboratory Workflow and Performance

3. Preanalysis

4. Analysis: Principles of Instrumentation

5. Analysis: Clinical Laboratory Automation

6. Point-of-Care Testing and Physician Office Laboratories

7. Postanalysis: Medical Decision Making

8. Interpreting Laboratory Results

9. Laboratory Statistics

10. Quality Control

11. Clinical Laboratory Informatics

12. Financial Management

13. Biological, Chemical and Nuclear Terrorism: Role of the Laboratory

Part 2: Clinical Chemistry

1. Evaluation of Renal Function, Water, Electrolytes and Acid-Base Function

2. Biochemical Markers of Bone Metabolism

3. Carbohydrates

4. Lipids and Dyslipoproteinemia

5. Cardiac Injury, Atherosclerosis, and Thrombotic Disease

6. Specific Proteins

7. Clinical Enzymology

8. Evaluation of Liver Function

9. Laboratory Diagnosis of Gastrointestinal and Pancreatic Disorders

10. Toxicology and Therapeutic Drug Monitoring

11. Evaluation of Endocrine Function

12. Reproductive Function and Pregnancy

13. Vitamins and Trace Elements

14. Chemical Basis for Analyte Assays and Common Interferences

Part 3: Urine and Other Bodily Fluids

1. Basic Examination of Urine

2. Cerebrospinal, Synovial, Serous Body Fluids, and Alternative Specimens

Part 4: Hematology and Transfusion Medicine

1. Basic Examination of Blood and Bone Marrow

2. Hematopoiesis

3. Erythrocytic Disorders

4. Leukocytic Disorders

5. The Flow Cytometric Evaluation for Hematopoietic Neoplasia

6. Immunohematology

7. Transfusion Medicine

8. Hemapheresis

9. Tissue Banking and Progenitor Cells

Part 5: Hemostasis and Thrombosis

1. Coagulation and Fibrinolysis

2. Platelet Disorders and Von Willebrand Disease

3. Laboratory Approach to Thrombotic Risk

4. Antithrombotic Therapy

Part 6: Immunology and Immunopathology

1. Overview of the Immune System and Immunologic Disorders

2. Immunoassays and Immunochemistry

3. Laboratory Evaluation of the Cellular Immune System

4. Laboratory Evaluation of Immunoglobin Function and Humoral Immunity

5. Mediators of Inflammation: Complement

6. Mediators of Inflammation: Cytokines and Adhesion Molecules

7. Human Leukocyte Antigen: The Major Histocompatability Complex of Man

8. The Major Histocompatibility Complex and Disease

9. Immunodeficiency Disorders

10. Clinical and Laboratory Evaluation of Systemic Rheumatic Diseases

11. Vasculitis

12. Organ-Specific Autoimmune Diseases

13. Allergic Diseases

Part 7: Medical Microbiology

1. Viral Infections

2. Chlamydial, Rickettsial, and Mycoplasmal Infections

3. Medical Bacteriology

4. In Vitro Testing of Antimicrobial Agents

5. Spirochete Infections

6. Mycobacteria

7. Mycotic Diseases

8. Medical Parasitology

9. Specimen Collection and Handling for Diagnosis of Infectious Diseases

Part 8: Molecular Pathology

1. Introduction to Molecular Pathology

2. Molecular Diagnostics: Basic Principles and Techniques

3. Polymerase Chain Reaction and Other Nucleic Acid Amplification Technology

4. Hybridization Array Technologies

5. Applications of Cytogenetics in Modern Pathology

6. Establishing a Molecular Diagnostics Laboratory

7. Molecular Diagnosis of Genetic Diseases

8. Identity Analysis: Use of DNA Analysis in Parentage, Forensic, and Missing Persons Testing

9. Pharmacogenomics and Personalized Medicine

Part 9: Clinical Pathology of Cancer

1. Diagnosis and Management of Cancer Using Serologic and Tissue Tumor Markers

2. Oncoproteins and Early Tumor Detection

3. Molecular Diagnosis of Hematopoietic Neoplasms

4. Molecular Genetic Pathology of Solid Tumors

5. High-Throughput Genomic and Proteomic Technologies in the Post-Genomic Era

Appendices (Online Only)

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