PART I Molecular Bases for Stem and Cancer Cells Proliferation

1 An introduction to proliferation and migration of stem cells\nand cancer\nMicheli Mainardi Pillat, Talita Glaser, Telma Tiemi Schwindt and Henning Ulrich

2 The role of cell adhesions, cell junctions and extracellular\nmatrix in normal development and carcinogenesis\nAnderson K. Santos, Fernanda M. P. Tonelli, Daniel A. F. Silva, Kátia N. Gomes, Luiz O. Ladeira and Rodrigo R. Resende

3 The embryonic rest hypothesis of cancer development:150\nyears later\nMariusz Z. Ratajczak, Maciej Tarnowski, Sylwia Borkowska, Karol Serwin .

4 Are calcium channels more important than calcium influx for cell proliferation ?\nAnne-Sophie Borowiec, Gabriel Bidaux and Thierry Capiod

5 Role of calcium signaling in stem cells and cancer cells\nproliferation\nMaria Jimena Amaya, Vânia A. M. Goulart, Anderson K. Santos, Alexandre H. Kihara, Silvia Guatimosim, Rodrigo R. Resende .

6 Formation and function of lipid droplets in inflammation\nand cancer\nJoão P.B. Viola, André L.S. Cruz, Miriam B.F. Werneck, Patricia T. Bozza

7 The role of sphingolipids in modulating pluripotency of stem\ncells\nSalman B. Hosain, Ronald A. Hill, Yong-Yu Liu

PART II Signaling Pathways to Cancer Cells Fate

8 Signaling pathways of cbl-b and its role on peripheral t cell\ntolerance\nK Venuprasad

9 BH3-only proteins in cancer and apoptosis\nFabio Ghiotto, Claudya Tenca, Franco Fais and Silvia Bruno

10 Signaling pathways of mta family proteins as regulators of\ncancer progression and metastasis\nYasushi Toh, Garth L. Nicolson

11 Signalling pathways of beta-catenin/jnk on carcinogenesis\nEliana Kalakouti, Roya Babaei-Jadidi and Abdolrahman S. Nateri

12 The regulation of the jnk cascade and programmed cell death by\nnf- b: mechanisms and functions\nJason Bennett, Marta Moretti, Anil K. Thotakura, Laura Tornatore and Guido Franzoso

PART III Uncontrolled Physiology Process Guiding to Cancer Cells

13 Migration, metastasis and more: the role of chemokines in the\nproliferation, spreading and metastasis of tumors\nRolf Mentlein, Kirsten Hattermann and Janka Held-Feindt

14 Autophagy, cell death, and cancer\nMaryam Mehrpour, Ahmed Hamaï and Patrice Codogno

15 The duality of stem cells - double edged sword in tumour\nevolution and treatment\nUrska Tajnsek, Helena Motaln, Natasa Levicar , Ana Rotter and Tamara T.Lah

16 Glioblastoma stem cells and implications for chemoresistance\nSuzana A. Kahn, Ema Torrado, Dora Brites, Vivaldo Moura Neto

17 The tumor microenvironment as a transient niche: a modulator of\nepigenetic states and stem cell functions\nLorena E. Mora-Blanco, James B. Lorens, and Mark A. LaBarge

18 Tumor-associated neutrophils (tans)\nAndré Gustavo Oliveira, Rodrigo Guabiraba, Mauro Martins Teixeira and Gustavo Batista Menezes

19 MicroRNA control of apoptotic programs in cancer\nReena V. Kartha and Subbaya Subramanian

PART IV Therapeutic Strategies for Anticancer Treatment

20 Markers of cancer stem cells and their functions\nOlivier Gires

21 Cancer cell dormancy: potential therapeutic targets to eradicate\ncancer cells within the niche\nJessian L.Munoz, Jacqueline M. Park, Sarah A. Bliss, Pranela Rameshwar

22 Modulating apoptosis in cancer therapy with ultrasound and high\nintensity nanosecond electric pulses\nTinghe Yu, Minghe Wu, Ping Huang, Lina Hu

23 Targeting cell cycle for anticancer treatment and neuroprotection Yun Dai, Shuang Chen, Liang Yi, Minhui Xu