Part 1.- Definition, epidemiology, and pathogenesis\n.- Chapter 1: Definition of IPF (Question: Is the latest classification [ATS/ERS] satisfactory?).- Chapter 2: Epidemiology and risk factors of IPF (Question: Can we dare to ask, \"What are the possible causes?\").- Chapter 3: Acute exacerbation of IPF (Question: The concept was proposed in Japan, but why was it not recognized in western countries?).- Chapter 4: Pathogenesis (Question: Is abnormal repair of epithelial damage involved in the basic pathogenesis of this disease?)\n.- Part 2 Diagnosis\n.- Chapter 5: Specific serum markers of IPF (Question: What are the significances of KL-6, SP-A, and SP-D?).- Chapter 6: High-resolution CT of honeycombing and IPF/UIP (Question: To what extent can honeycomb lung be diagnosed by imaging? To what extent can IPF diagnosis be made by HRCT?).- Chapter 7: Pathology of IPF (Question: Why does the pathological classification of IIPs vary among pathologists?).- Chapter 8: Differential diagnosis (Question: What should we particularly keep in mind in the differential diagnosis?)\n.- Part 3 Management and prognosis\n.- Chapter 9 Pharmacotherapy of IPF (antifibrotic compounds) (Question: Can antifibrotic agents really inhibit fibrosis? How about the development of new therapeutic agents?).- Chapter 10: Pharmacotherapy of IPF (Corticosteroids, immunosuppressants) (Question: Are these actually effective? Ineffective? Harmful?).- Chapter 11: Non-pharmacological therapy for IPF (Question: Is respiratory care actually effective?).- Chapter 12: Pharmacotherapy of acute exacerbation of IPF (Corticosteroids, immunosuppressants and direct hemoperfusion with polymyxin B) (Question: Are high-dose steroid therapy, other immunosuppressant therapy, and PMX therapy [often used in Japan] really effective?)\n.- Part 4 Topics\n.- Chapter 13 :Combined pulmonary fibrosis and emphysema (CPFE) (Question:\nIs it an independent disease entity?).- Chapter 14: Common pathways in IPF and lung cancer (Question: Why is lung cancer associated with IPF at a high frequency?).- Chapter 15 :Acute exacerbation of IIPs after pulmonary resection for lung cancer (Question: Can acute exacerbation of IPF be predicted preoperatively?)