Part I Introduction.- History of Vascular Access.- Vascular Anatomy of Central and Peripheral Veins.- Type of Devices for Mid- and Long-term Venous Access.- Huber Needle: Different Types, Uses, Prevention of Accidents.- Part II Totally Implantable Access Devices.- Clinical Indications, Preoperative Assessment, Set-up and Organizational Aspects.- Choice of Venous Sites. Surgical Implant/Technique.- Choice of Venous Sites. Percutaneous Implant/Technique/US Guidance.- Modified Seldinger Technique for Open Central Venous Cannulation for Totally Implantable Access Device.- Optimal Catheter Tip Position: Radiologic Criteria and Clinical Relevance.- Verifying Catheter Tip Position: Fluoroscopy vs Intravasal Electrogram.- Part III Immediate Complication: Prevention and Treatment.- Pneumothorax.-Hemothorax.- Air Embolism.- Accidental Arterial Puncture.- Cardiac Arrhythmia.- Heart Tamponade.- Brachial Plexus Injury.- Part IV Early Complications: Diagnosis and Treatment.- Hemoptysis.- Pocket Hematoma.- Wound Dehiscence.- Reversal.- Part V Late Complications.- Catheter-related Bloodstream Infection.-Thrombosis.- Superior Vena Cava Erosion and Perforation.-Catheter Obstruction.- Catheter Rupture.- Catheter Migration.- Catheter Embolization.- Withdrawal Obstruction.-Skin Necrosis.- Extravasation.- Pocket Infection.- Nursing of Vascular Access: Highlights of Hot Issues.- Power Technology: How to Safely Use Ports and Central Catheters to Deliver Contrast Medium in Radiology Procedures.- Removal of Totally ImplantableVenous Access Device.- Cost Issues.- Quality of Life and Patients Satisfaction.- Legal Aspects.- Future Investigation.