Anatomy and Normal Histology of the Prostate Pertinent to Biopsy Practice.- Prostate Needle Biopsy Sampling Techniques: Impact on Pathological Diagnosis.- Diagnosis of Limited Cancer in Prostate Biopsy.- Immunohistochemistry in Prostate Biopsy Evaluation.- Contemporary Approach to Gleason Grading of Prostate Cancer.- Histologic Variants of Prostate Carcinoma.- Benign Mimics of Prostate Carcinoma.- Atypical Cribriform Lesions in Prostate Biopsy: Relationship to Prostate Carcinoma, Differential Diagnosis, and Emerging Concepts of Intraductal Carcinoma of the Prostate.- High-Grade Prostatic Intraepithelial Neoplasia.- Atypical Glands Suspicious for Cancer.- Spindle Cell Lesions of the Prostate Gland.- Treatment Effect in Benign and Malignant Prostate Tissue.- Molecular Biology of Prostate Cancer and Emerging Diagnostic and Prognostic Biomarkers.- Biopsy Specimen Handling, Processing, Quality Assurance Program.- Reporting of Prostate Biopsy.