Preface.- Contents.- Note on Nomenclature.- Author Addresses.- Section 1Historical Introduction to Secreted Cell Stress Proteins as Signalling Proteins.- Chapter 1 Discovery of the Cellular Secretion of Cell Stress Proteins, Larry Hightower and Emily J. Noonan.- Chapter 2 Discovery of the Agonist Activities of Molecular Chaperones and Protein-Folding Catalysts, Brian Henderson.- Chapter 3 Identification of Cell Stress Proteins in Biological Fluids, A. Graham Pockley.- Section 2 Intracellular Trafficking of Molecular Chaperones and its Consequences.- Chapter 4 Hsp27 Phosphorylation Patterns and Cellular Consequences, Sergiy Kosteonko and Ugo Moens.- Chapter 5 Evidence on Cholesterol-Controlled Lipid Raft Interaction of the Small Heat Shock Protein HSPB11, Zsolt Török, Ana-Maria Pilbat, Imre Gombos, Enikö Hocsak, Balázs Sümegi, Ibolya Horváth and László Vígh.- Chapter 6 Hsp70 Chaperone Systems in Vesicular Trafficking, David A. Parfitt, Daniel C. Campbell and J. Paul Chapple.- Chapter 7 Pathways of Hsp70 Release: Lessons from Cytokine Secretion, Ayesha Murshid and Stuart K Calderwood.- Chapter 8 Nucleolin: A Novel Intracellular Transporter of HSPA1A, Punit Kaur, Appukuttan R Pradeep and Alexzander Asea.- Chapter 9 The Hsp90-Based Protein Trafficking System and Linkage to Protein Quality Control, William B. Pratt, Yoshihiro Morishima, Andrew P. Lieberman, and Yoichi Osawa.- Section 3 Molecular Chaperones as Cell Surface Receptors and Receptor Ligands.- Chapter 10 Cell Surface Molecular Chaperones and the LPS Receptor, Kathy Triantafilou.- Chapter 11 Hsp60: An Unexpected Cell Surface Receptor in Prokaryotes and Eukaryotes, Brian Henderson.- Chapter 12 Pathophysiological Barriers Impeding the Delivery of Heat Shock Protein (HSP)-based Macromolecules and Nanotherapeutics to Solid Tumors, Peter Vaupel and Gabriele Multhoff.- Chapter 13 The Chaperokine Activity of HSPA1A, Punit Kaur and Alexzander Asea.- Chapter 14 Molecular Chaperones and Scavenger Receptors: Binding and Trafficking of Molecular Chaperones by Class F and Class H Scavenger Receptors, Ayesha Murshid, Jianlin Gong and Stuart K Calderwood.- Chapter 15 Grp78 (BiP): A Multifunctional Cell Surface Receptor, Mario Gonzalez-Gronow, Salvatore V. Pizzo and Uma K. Misra.- Section 4 Extracellular Secretion of Molecular Chaperones in Prokaryotes and Eukaryotes.- Chapter 16 Mycobacterium Tuberculosis Hsp60 as a Key Virulence Factor in Tuberculosis, Richard W. Stokes.- Chapter 17 Hsp90 vs Conventional Growth Factors in Acute and Diabetic Wound Healing, Wei Li, Kathryn O'Brien, David T. Woodley and Mei Chen.- Chapter 18 Circulating Molecular Chaperones in Health and Disease, Zoltán Prohászka.- Index