Part I. Chapter. 1 HSCT: Historical perspective Storb, R Chapter. 2 The EBMT: History, present & future Apperley, J; Gratwohl, A; Mohty, M Chapter. 3 The donor registries (organization, regulation, international search...) Madrigal, A; Evseeva, Irina Chapter. 4 The HSCT Unit (minimal requirements, data manager trasplant coordinator) Aljurf, M; Niederwieser, Dietger; Rasheed, Walid Chapter. 5 JACIE accreditation of HSCT programs Saccardi, R Chapter. 6 Statistics in HSCT and Cellular Therapies Labopin, M; Iacobelli, S; de Wreede, Liesbeth; Szydlo, Richard Part II. Chapter. 7 Biological properties of HSC: scientific basis for HSCT Chabannon, C ; Aiuti, M Chapter. 8 Biological properties of cells other than HSC (adaptative, abT, Treg, DC. Innete gdT, IELs MSC, NK) Toubert, A; Koehl, U; Bondanza, A Chapter. 9 Histocompatibility (main concepts on HLA) K. Fleischhauer; Spierings Chapter. 10 Clinical & biological concepts for mastering Immune reconstitution after HSCT Boelens, J; Kuball, J Part III. Chapter. 11 Evaluation and counselling of candidates Rambaldi, A Chapter. 12 Donor selection for adults and pediatrics Ayuk, F; Balduzzi, A Chapter. 13 Conditioning (MAC, RIC, NMA; including TBI) Nagler, A Chapter. 14 Bone marrow harvest Gorin, Claude Chapter. 15 Mobilization and collection of HSC Hübel, K Chapter. 16 Collection of HSC in children Peters, C; Witt, Volker Chapter. 17 Processing, cryopreserving, and controlling the quality of HSC Wuchter, Patrick Chapter. 18 Procurement and management of cord blood Rocha, V; Querol, S Chapter. 19 Graft manipulation Handgretinger, R Chapter. 20 Documentation of engraftment and chimerism after HSCT Bader, P Chapter. 21 Short and long term controls after HSCT Shimoni, A Part IV. Chapter. 22 Vascular access Cesaro, S Chapter. 23 Transfusion support Schrezenmeier, H Chapter. 24 Fluid and electrolyte management Masszi, T; Baumgartner, Annic Chapter. 25 GVHD prophylaxis (immunosuppression) Socié, G Chapter. 26 Management ATG (SIRS) F. Bonifazi Chapter. 27 Infections control and isolation procedures Mikulska, M Chapter. 28 Pain management Ahmedzai, SH Chapter. 29 Specific aspects of management in children Castagnola, Elio; Riccardi, F Chapter. 30 Vaccinations de la Cámara, Rafa Chapter. 31 Psychological support Moreno, E ; Schulz-Kindermann, F ; Polomeni, Alice Chapter. 32 Relevant pharmacological interaction Bauters, T Chapter. 33 Role of nursing in HSCT Babic, A; Murray, J Chapter. 34 Ethical issues in HSCT Dalle, JH; El-Ghariani, K Part V. Chapter. 35 Quality assessment of life after HSCT for pediatric and adults Barata, Anna; Jim, Heather Chapter. 36 Neutropenic fever Mikulska, M Chapter. 37 Bacterial infections Averbuch, D Chapter. 38 Invasive fungal infections Maertens, J Chapter. 39 Viral infections (CMC, EVB, VZV, HSV, HHV6, Resp. V, HCV, HBV...) & anti-viral cell therapy Ljungman, P; Styczynski, J; Einsele, Hermann Chapter. 40 Other infections in HSCT (Tuberc, Toxo, PCJ, Noc, List.) Martino, R Chapter. 41 Bleeding and thrombotic complications Savani, B Chapter. 42 Graft failure Valcárcel , D; Sureda, A Chapter. 43 Early complications of endothelial origin Carreras, E Chapter. 44 Acute GvHD Greinix, H; Holler, E; Zeiser, R Chapter. 45 Chronic GvHD Wolff, D; Lawitschka, A Chapter. 46 Post-transplant lymphoproliferative syndromes Styczynski, J ; Giebel, S Chapter. 47 Iron overload Angelucci, E Chapter. 48 Secondary neoplasia (other than PTLPS) Tichelli, A Part VI. Chapter. 49 Specific organ complications: Ocular / oral / pulmonary / hepatic Ruutu, T; Hashmi, S Chapter. 50 Gastrointestinal complications Basak, G Chapter. 51 Hemorrhagic cystitis and renal dysfunction Cesaro, S Chapter. 52 Pulmonary complications Carreras, E Chapter. 53 Neurological complications Duléry, R Chapter. 54 Specific organ complications: Skin, hair, musculoskeletal Ayuk, F; Savani, B Chapter. 55 Cardiovascular diseases and metabolic syndrome Snowden, J; Greenfield, D Chapter. 56 Endocrine, fertility a