Introduction to oral premalignant lesions including epidemiology.- Development, relevant anatomy and physiology of the oral cavity and mucosa.- Basic cellular and molecular biology to include the effects of carcinogens (smoking, alcohol, betel nut, HPV, chronic candida).- Pathophysiology of the transformation from normal mucosa to invasive malignancy (carcinogenesis) including dysplasia.- Leukoplakia including benign lesions.- Erythroplakia and erythroleukoplakia.-The lichenoid group of diseases including erosive and atrophic lichen planus.-Systemic diseases that are potentially pre-cancerous (iron deficiency anaemic, immunosuppression.- Clinical presentation of oral mucosal premalignant lesions (this will be a larger section), and include high and low risk lesions.- Diagnosis including biopsy techniques and other relevant investigations.- Management of premalignant disease of the oral mucosa with up to date clinical trials and adjuvant therapies. Role of surgery, laser treatments.- The future. ukryj opis