Braun, Matthias, Schickl, Hannah, Dabrock, Peter Introduction I. Mapping the current scientific state of the art and the legal framing Drucker, Micha Genome Editing: The current scientific state of the art Lunshoff, Jeantine Gene Editing in context. Thoughts from the bench side Rixen Stephan Genome Editing: The current international legal framing Molnár-Gábor, Fruzsina Incorporating ethics into law or law into ethics? Considerations on uniting normative standards for the regulation of genome editing on an international level

II. Theoretical Challenges Schickl, Hannah Gene Editing. Game changer for ethical reasoning? Birnbacher, Dieter Which Role and Meaning should be ascribed to Safety Arguments in Debating CRISPR? Rothaar, Markus Gene Editing and cross species entities. Is there an ethical relevance of species membership? Omerbasic, Alina Gene editing, non-identity and the notion of harm Primc, Nadia Human reproduction. 'Nature' as the object of technoscience Wirth, Mathias Transition and Care. Theological Concepts of Dynamic Creation and Ethics of Gene Editing Rubeis, Giovanni Germline genome-editing as a therapeutic perspective. Bioethical implications Cavaliere, Giulia Genome editing and reproduction: curing embryos, society or prospective parents?

III. Towards a Governance Frame in dealing with Genome Editing Dabrock, Peter The Fragility of Public Trust in Scientific Research: The Case of Genome Editing Kaelin, Lukas Debating Genome Editing Technologies. Questioning the Role of Public Discussion Friele, Minou When to end the moratorium? Typology of argumentation pro and con CRISPR/Cas9 ene editing research in human embryos Odzuck, Eva The legitimacy of gene editing - a political theory of the body and the human genome and its policy implications Braun, Matthias Ethical and Governmental Challenges in Dealing with Genome Editing